Journal: Scientific Reports
Article Title: Meniscus surface texture is associated with degenerative changes in biological and biomechanical properties
doi: 10.1038/s41598-022-16206-2
Figure Lengend Snippet: Relationship between surface integrity grade and OA-related cytokines. A total of 114 samples from 19 human menisci were included in each study. ( A ) Level of gene expression. ( B ) Protein concentration before IL-1β stimulation. ( C ) Comparison of protein concentration before and after IL-1β stimulation. ( D ) Change in protein concentration. * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001. Values are shown as mean ± SEM.
Article Snippet: Human recombinant interleukin (IL) -1β (5 ng/ml; R&D Systems, Minneapolis, MN, USA) was added 6 days after the start of explant culture.
Techniques: Gene Expression, Protein Concentration, Comparison